At a glance
- Shetland Sheepdogs are generally healthy but prone to specific genetic conditions including hip dysplasia, Collie Eye Anomaly, and dermatomyositis
- Early detection through regular vet exams and genetic screening can prevent or manage most health issues effectively
- Weight management and proper nutrition are critical for preventing joint problems and extending lifespan
- The MDR1 gene mutation affects medication sensitivity and requires genetic testing to ensure safe treatment
Understanding your Sheltie's genetic predispositions
Many Shetland Sheepdog owners worry when they first learn about breed-specific health concerns, but knowledge becomes your greatest tool for prevention. These intelligent, long-lived dogs typically enjoy 12 to 14 years of good health when owners understand what to watch for and take proactive steps.
The most significant health issues in Shelties stem from their genetics. Hip dysplasia affects joint development, potentially causing limping and difficulty rising as your dog ages. Collie Eye Anomaly can lead to vision problems, sometimes detected as early as puppyhood through specialised eye exams. Perhaps most concerning is dermatomyositis, sometimes called Sheltie Skin Syndrome, which causes crusty lesions on the face and ears, and in severe cases, muscle deterioration.
Research shows that responsible breeding significantly reduces these conditions. Always ask breeders for health clearances on both parents, including OFA or PennHIP screening for hips, CERF eye examinations, and genetic tests for CEA, MDR1, and von Willebrand's disease. Reputable breeders will readily provide this documentation.
Recognising early warning signs

You might notice subtle changes in your dog's behaviour before obvious symptoms appear. A Shetland Sheepdog developing hip dysplasia may start favouring one leg or show reluctance to climb stairs. The characteristic "hopping" gait often becomes apparent during middle age, typically around five to seven years.
Vision changes require immediate attention. Dogs with Collie Eye Anomaly may bump into objects or seem hesitant in dim lighting. Since this condition often appears in puppies, early ophthalmologic screening becomes essential for any breeding program.
Skin issues present differently across individual dogs. Dermatomyositis typically begins with small, crusty lesions around the face, ears, or feet. These dogs often show increased sensitivity to sunlight, and owners may notice their pet avoiding bright outdoor areas. In severe cases, muscle atrophy develops, particularly affecting the jaw muscles and making chewing difficult.
Thyroid disease manifests through seemingly unrelated symptoms. Unexplained weight gain, lethargy, hair loss, or recurring skin problems often signal thyroid dysfunction. Annual thyroid screening becomes particularly important for middle-aged Shelties, as early intervention prevents more serious complications.
The MDR1 gene mutation dilemma
Perhaps no other genetic issue requires more immediate attention than the MDR1 gene mutation. This condition affects how your dog processes certain medications, making standard treatments potentially dangerous. Dogs with this mutation can experience severe neurological symptoms when exposed to common drugs like ivermectin, found in many heartworm preventatives.
Genetic testing for MDR1 should happen early in your dog's life, ideally during puppyhood. Once you know your dog's status, inform every veterinarian, emergency clinic, and boarding facility. Keep documentation readily available, as this information becomes critical during any medical emergency.
Many Shetland Sheepdog owners discover this mutation only after their dog experiences adverse reactions. Prevention through testing costs significantly less than emergency treatment and provides peace of mind for routine veterinary care.
Managing joint health throughout life

Joint problems in Shelties extend beyond hip dysplasia to include elbow dysplasia and patellar luxation. You'll often see patellar luxation as an intermittent "skipping" gait, where your dog holds up a hind leg briefly before continuing normally. This condition ranges from mild to severe, with surgical correction needed for the most serious cases.
Weight management becomes your most powerful tool for joint health. Even slightly overweight dogs experience increased stress on their joints, accelerating arthritis development. Measure your dog's food portions rather than estimating, and limit treats to no more than 10% of daily calories.
Joint supplements like Dasuquin or Cosequin show moderate effectiveness, particularly when started before symptoms appear. These over-the-counter options contain glucosamine and chondroitin, which support cartilage health. Omega-3 fatty acids from fish oil provide additional anti-inflammatory benefits for both joints and skin.
Preventing and treating skin conditions
Regular grooming serves dual purposes for Shetland Sheepdogs, preventing matting while allowing early detection of skin problems. Dermatomyositis requires particularly vigilant monitoring, as researchers haven't identified a specific genetic marker for testing. This means breeding decisions rely on family history and clinical observation.
Dogs with dermatomyositis benefit from limited sun exposure and specialised topical treatments. Vetericyn Plus Antimicrobial Hydrogel helps with minor lesions, while severe cases require prescription immunosuppressive medications. Work closely with your veterinarian to balance treatment benefits against potential side effects.
Allergic skin conditions, or atopy, present differently than dermatomyositis but cause similar discomfort. These dogs typically show intense itching, recurrent ear infections, and seasonal flare-ups. Management options include hypoallergenic diets, medications like Apoquel or Cytopoint, and sometimes immunotherapy for severe cases.
Heart health and emergency conditions
While less common than joint or skin problems, heart conditions in Shelties require immediate attention. Patent ductus arteriosus (PDA) and other congenital heart defects may cause coughing, difficulty breathing, or exercise intolerance. Regular cardiac examinations during routine vet visits help detect these conditions early.
Gallbladder mucocele represents a potentially life-threatening emergency that affects some Shelties. This condition causes sudden illness with vomiting, lethargy, and often jaundice. Unlike gradual-onset conditions, gallbladder mucocele requires immediate veterinary intervention and possible emergency surgery.
Von Willebrand's disease affects blood clotting, making routine procedures potentially dangerous. Genetic testing identifies carriers before breeding, while affected dogs require special preparation for any surgery or dental work. Inform your veterinarian about this condition before scheduling any procedures.
Creating a prevention-focused health plan
Annual veterinary examinations form the foundation of preventive care, but Shetland Sheepdogs benefit from more targeted screening. Thyroid testing should begin around age four and continue annually. Eye examinations help monitor for progressive conditions, while cardiac screening detects heart problems before symptoms appear.
Dental care prevents periodontal disease, which affects over 80% of dogs by age three. Brush your dog's teeth regularly using CET Enzymatic Toothpaste, and consider dental treats like Greenies between professional cleanings. Poor dental health contributes to heart and kidney problems as dogs age.
Epilepsy affects some Shelties, typically appearing between one and five years of age. While frightening to witness, most seizures respond well to medications like phenobarbital or potassium bromide. Keep a seizure log noting frequency, duration, and potential triggers to help your veterinarian adjust treatment.
Hearing loss becomes more common as Shelties age, making early hand signal training valuable for all dogs. Start incorporating visual cues alongside verbal commands during puppyhood, creating a communication system that remains effective throughout your dog's life.
Obesity prevention requires consistent effort but pays significant dividends in health and longevity. Over 20% of Shelties become overweight without proper management, leading to increased risks for joint disease, heart problems, and diabetes. Regular exercise, portion control, and avoiding excessive treats keep your dog at optimal weight throughout their 12 to 14-year lifespan.