Can Probiotics Help Dogs With Separation Anxiety?
5 min read
Last updated on August 11, 2025

Can Probiotics Help Dogs With Separation Anxiety?

Learn how specific probiotic strains reduce separation anxiety behaviours. Discover research findings and the importance of veterinary consultation for treatment.

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The distressed whining, destructive behaviour, and endless pacing when you leave the house – these are telltale signs your dog is struggling with separation anxiety. As loving pet owners, watching our furry friends suffer from this condition can be heart-wrenching, especially when it affects their quality of life and your peace of mind. While traditional behavioural training remains important, emerging research suggests an unexpected ally in managing canine separation anxiety: .

Understanding Separation Anxiety in Dogs

Separation anxiety is more than just missing you while you're gone. It's a complex behavioural issue that can manifest in various concerning ways. From excessive barking and destructive chewing to inappropriate toileting and escape attempts, these behaviours often intensify over time if left unaddressed. The stress your dog experiences during these episodes isn't just emotional – it triggers physical responses, including elevated heart rate and increased cortisol levels, which can impact their overall health.

Recent scientific discoveries have revealed fascinating insights into how the influences your dog's emotional wellbeing. This connection explains why probiotics – beneficial bacteria typically associated with digestive health – might help manage anxiety-related behaviours.

The gut-brain axis serves as a crucial communication highway between your dog's digestive system and their brain. When this system is balanced, it helps regulate mood and behaviour. However, stress can disrupt this delicate balance, creating a cycle where anxiety affects gut health, and poor gut health, in turn, intensifies anxiety symptoms.

A dog lying comfortably on a soft bed, conveying a sense of calmness and safety for dogs with separation anxiety

How Probiotics Can Help

Understanding how probiotics reduce anxiety in dogs opens up new possibilities for managing separation anxiety. These beneficial bacteria work through multiple mechanisms to help calm your anxious pet:

1. Neurotransmitter Production

Probiotics can influence the production of mood-regulating chemicals, such as serotonin and gamma-aminobutyric acid (GABA), helping to promote a more balanced emotional state.

2. Stress Response Regulation

Specific probiotic strains, such as Lactiplantibacillus plantarum PS128 and Bifidobacterium longum BL999, have been shown to help lower cortisol levels and heart rates in dogs experiencing anxiety-provoking situations.

3. Inflammatory Response

By supporting a through improved digestion, probiotics help reduce inflammation that might contribute to anxiety-like behaviours.

Research-Backed Results

Recent studies have shown promising results in using probiotics for anxiety management in dogs. For instance, research published in Applied Animal Behaviour Science found that Lactiplantibacillus plantarum PS128 significantly reduced aggression and separation anxiety in dogs after just 14 days of supplementation.

Additionally, a study by the Purina Institute found that Bifidobacterium longum BL999 helped reduce anxious behaviours such as excessive barking, jumping, and spinning, while also lowering salivary cortisol levels.

Practical Steps for Implementation

While probiotics show promise, they work best as part of a comprehensive approach to managing separation anxiety. Here's how to maximise their effectiveness:

Start Gradually

Introduce probiotics slowly into your dog's routine to allow their system to adjust. This helps prevent any digestive upset and ensures better absorption of the beneficial bacteria.

Maintain Consistency

Regular administration is key – probiotics need time to colonise and establish themselves in your dog's gut to provide optimal benefits.

Monitor Progress

Keep a journal of your dog's behaviour to track improvements. Look for changes in:

  • Frequency and intensity of anxiety episodes
  • Recovery time after you return home
  • General demeanour and stress levels
  • Sleep patterns and appetite

Supporting Strategies

While can help manage separation anxiety, combining them with these practical strategies often yields the best results:

Environmental Enrichment

Create a comforting space for your dog when alone, including:

  • A quiet, secure area with familiar bedding
  • Calming music or white noise
  • Interactive toys for mental stimulation

Exercise and Mental Stimulation

Ensure your dog receives adequate physical activity and mental engagement before you leave, helping to naturally tire them and reduce anxiety.

Desensitisation Training

Gradually accustom your dog to your absence through short departures, slowly increasing the duration as they become more comfortable.

A veterinarian consulting with a dog owner about probiotics for managing separation anxiety

When to Seek Professional Help

While understanding the is important, some situations require additional support. Consult your veterinarian if:

  • Your dog's anxiety seems severe or is worsening
  • They're causing harm to themselves or your property
  • Other health issues might be contributing to their anxiety
  • You're unsure about the best probiotic options for your dog's specific needs

The Path Forward

Managing separation anxiety requires patience and a multi-faceted approach. While probiotics offer a promising natural intervention, they work best when combined with appropriate training, environmental management, and professional guidance when needed. Every dog is unique, so results may vary.

Always consult with your veterinarian before starting any new supplement regimen, including probiotics. They can help determine the most appropriate approach for your dog's specific situation and ensure any interventions are safe and effective.

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Frequently Asked Questions

Research suggests that certain probiotic strains, particularly Lactiplantibacillus plantarum PS128 and Bifidobacterium longum BL999, may help reduce anxiety-related behaviours in dogs. However, more studies are needed to fully understand their effectiveness, and you should always consult your veterinarian before starting any supplementation.
The time frame for seeing results can vary between individual dogs. Generally, it may take 4-8 weeks of consistent probiotic supplementation before noticing improvements in anxiety-related behaviours. Maintaining a regular dosing schedule and combining probiotics with behavioural training often yields the best results.
Probiotics are generally considered safe for dogs when used as directed. However, it's essential to choose a high-quality supplement specifically formulated for dogs and to consult with your veterinarian before starting any new supplement regimen, especially if your dog has existing health conditions or is taking other medications.
In addition to probiotics, several natural approaches can help manage separation anxiety in dogs. These include regular exercise, behaviour modification training, calming music, anxiety wraps or shirts, and creating a safe, comfortable space. Some dogs may also benefit from other natural supplements like L-theanine or chamomile, but always discuss these options with your veterinarian first.

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